Assessment of efficacy of trastuzumab (Herceptin) comprising adjuvant therapy of HER2+ breast cancer patients determined based upon statistical analysis of overall survival (OS) and disease-free survival (PFS)

  • Beata Jagielska Maria Sklodowska-Curie Memorial Cancer Centre and the Institute of Oncology, Warsaw
  • Andrzej Czubek Chamber of Commerce "Polish Medicine"
  • Konrad Talasiewicz Maria Sklodowska-Curie Memorial Cancer Centre and the Institute of Oncology, Warsaw,
  • Adam Twarowski Maria Sklodowska-Curie Memorial Cancer Centre and the Institute of Oncology, Warsaw
  • Piotr Rutkowski Maria Sklodowska-Curie Memorial Cancer Centre and the Institute of Oncology, Warsaw
  • Maciej Krzakowski Maria Sklodowska-Curie Memorial Cancer Centre and the Institute of Oncology, Warsaw
  • Bianka Kathryn Saetre Phoenix Biomolecular Engineering Foundation,
  • Marek Malecki 6Genomics Laboratories, Phoenix Biomolecular Engineering Foundation
Keywords: breast cancer, trastuzumab, Herceptin, radiotherapy, chemotherapy, immunotherapy, hormonal therapy, adjuvant therapy, human epidermal growth factor receptor-2, estrogen receptor, progesterone receptor, overall survival, disease-free survival

Abstract

Abstract: In patients suffering from breast cancer, adjuvant radiation, chemotherapy, or immunotherapy, which immediately follow the surgery as the first line therapy, greatly improve overall (OS) and disease-free survival (DFS). Various regimens of adjuvant therapy for these patients have been tested contingent upon the clinical staging. Inclusion of adjuvant immunotherapy is particularly promising.

 

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Published
2018-08-01
How to Cite
Jagielska, B., Czubek, A., Talasiewicz, K., Twarowski, A., Rutkowski, P., Krzakowski, M., Saetre, B., & Malecki, M. (2018). Assessment of efficacy of trastuzumab (Herceptin) comprising adjuvant therapy of HER2+ breast cancer patients determined based upon statistical analysis of overall survival (OS) and disease-free survival (PFS). <font Color="white">Molecular and Cellular Therapies</Font&gt;, 2018(1), 1-12. https://doi.org/10.26781/2052-8426-2018-02
Section
Research Article