DNA Hybridization Detection based on Plasmonic Photonic Crystal Fiber

Authors

  • Mohammad Y. Azab Faculty of Engineering, Mansoura University Mansoura, Egypt, Mansoura, 35516, Egypt
  • Abed M. Nasr Faculty of Engineering, Mansoura University Mansoura, Egypt, Mansoura, 35516, Egypt
  • S. S. A. Obayya Faculty of Engineering, Mansoura University Mansoura, Egypt, Mansoura, 35516, Egypt
  • Mohamed Farhat O. Hameed Faculty of Engineering, Mansoura University Mansoura, Egypt, Mansoura, 35516, Egypt,Centre for Photonics and Smart Materials Zewail City of Science and Technology, October Gardens, 6th of October City, Giza 12578, Egypt ,Nanotechnology and Nanoelectronics Engineering Program Zewail City of Science and Technology, October Gardens, 6th of October City, Giza 12578, Egypt

Keywords:

D-shaped fiber, DNA hybridization, photonic crystal fiber, plasmonic biosensor

Abstract

A novel design of surface plasmon (SP) photonic crystal fiber (PCF) for DNA hybridization detection is proposed and analyzed. The suggested biosensor relies on plasmonic D-shaped PCF configuration. Accordingly, the core guided mode in the silica core is coupled with the SP mode near the plasmonic layer. The resonance wavelength is sensitive to the DNA hybridization process. Therefore, the suggested bio-sensor is studied to maximize the DNA hybridization detection sensitivity by adjusting the structural geometrical parameters. The numerical results are obtained using full vectorial finite element method with perfectly matched layer boundary condition and non-uniform meshing capabilities. The reported Dshaped PCF offers high wavelength sensitivity of 405.4 nm/RIU with a corresponding amplitude sensitivity of 5.65 RIU−1. Consequently, the applications based on DNA classification can be potentially implemented by the reported biosensor.

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References

P. J. Sazio, A. Amezcua-Correa, C. E. Finlayson, J.

R. Hayes, T. J. Scheidemantel, N. F. Baril, B. R. Jackson, D. J. Won, Zhang, F. Margine, E. R. V. Gopalan, V. H. Crespi, and J. V. Badding, “Micro- structured optical fibers as high-pressure micro- fluidic reactors,” Science, vol. 311, no. 5767, pp. 1583-1586, Mar. 2006.

M. Y. Azab, M. F. O. Hameed, and S. S. A. Obayya, “Multi-functional optical sensor based on plasmonic photonic liquid crystal fibers,” Opt. Quant. Electron., vol. 49, no. 2, pp. 1-17, Jan. 2017.

A. A. Rifat, R. Ahmed, A. K. Yetisen, H. Butt, A. Sabouri, G. A. Mahdiraji, S. H. Yun, and F. R. M. Adikan, “Photonic crystal fiber based plasmonic sensors,” Sensor. Actuator. B Chem., vol. 243, pp. 311-325, May 2017.

T. Dar, J. Homola, B. M. A. Rahman, and M. Rajarajan, “Label-free slot-waveguide biosensor for the detection of DNA hybridization,” Applied Optics, vol. 51, no. 34, pp. 8195-8202, Nov. 2012.

M. J. Yin, C. Wu, L. Y. Shao, W. K. E. Chan,

A. P. Zhang, C. Lu, and H. Y. Tam, “Label-free, disposable fiber-optic biosensors for DNA hybridization detection,” Analyst, vol. 138, no. 4, pp. 1988-1994, Jan. 2013.

S. Ahn, D. S. Freedman, X. Zhang, and M. S. Unlü, “High-throughput label-free detection of DNA hybridization and mismatch discrimination using interferometric reflectance imaging sensor,” Methods in Molecular Biology, vol. 1039, pp. 181- 200, July 2013.

C. Viphavakit, M. Komodromos, C. Themistos, W.

S. Mohammed, K. Kalli, and B. M. A. Rahman, “Optimization of a horizontal slot waveguide biosensor to detect DNA hybridization,” Applied Optics, vol. 54, no. 15, pp. 4881-4888, May 2015.

Y. Cao, T. Guo, X. Wang, D. Sun, Y. Ran, X. Feng, and B. O. Guan, “Resolution-improved in situ DNA hybridization detection based on microwave photonic interrogation,” Opt. Express, vol. 23, no. 21, pp. 27061-27070, Oct. 2015.

R. Gao, D. F. Lu, J. Cheng, Y. Jiang, L. Jiang, J. D. Xu, and Z. M. Qi, “Fiber optofluidic biosensor for the label-free detection of DNA hybridization and methylation based on an in-line tunable mode coupler,” Biosensors and Bioelectronics, vol. 15, no. 86, pp. 321-329, Dec. 2016.

D. Sun, T. Guo, and B. O. Guan, “Label-free detection of DNA hybridization using a reflective microfiber Bragg grating biosensor with self- assembly technique,” Journal of Lightwave Technology, vol. 35, no. 16, pp. 3354-3359, Aug. 2017.

M. Y. Azab, M. F. O. Hameed, A. M. Nasr, and

S. S. A. Obayya, “Label free detection for DNA hybridization using surface plasmon photonic

crystal fiber biosensor,” Optical and Quantum Electronics, vol. 50, no. 68, pp. 1-13, Jan. 2018.

S. Kaye, Z. Zeng, M. Sanders, K. Chittur, P. M. Koelle, R. Lindquist, U. Manne, Y. Lin, and J. Wei, “Label-free detection of DNA hybridization with a compact LSPR-based fiber-optic sensor,” Analyst, vol. 142, pp. 1974-1981, Apr. 2017.

M. F. O. Hameed, A. S. Saadeldin, E. M. A. Elkaramany, and S. S. A. Obayya, “Label-free highly sensitive hybrid plasmonic biosensor for the detection of DNA hybridization,” Journal of Lightwave Technology, vol. 35, no. 22, pp. 4851- 4858, Nov. 2017.

S. S. A. Obayya, B. M. A. Rahman, and H. A. El- Mikati, “New full-vectorial numerically efficient propagation algorithm based on the finite element method,” Journal of Lightwave Technology, vol. 18, no. 3, pp. 409-415, Mar. 2000.

S. S. A. Obayya, B. M. A. Rahman, K. T. V. Grattan, and H. A. El-Mikati, “Full vectorial finite- element-based imaginary distance beam propagation solution of complex modes in optical waveguides,” Journal of Lightwave Technology, vol. 20, no. 6, pp. 1054-1060, June 2002.

COMSOL Multiphysics® [Online] Available: http://www.comsol.com. COMSOL AB, Stockholm, Sweden”

A. D. Rakic, A. B. Djurisic, J. M. Elazar, and M.

L. Majewski, “Optical properties of metallic films for vertical-cavity optoelectronic devices,” Applied Optics, vol. 37, no. 22, pp. 5271-5283, Aug. 1998.

P. Russell, “Photonic crystal fibers,” Science, vol. 299, no. 5605, pp. 358-362, Jan. 2003.

V. M. N. Passaro and M. La-Notte, “Optimizing SOI slot waveguide fabrication tolerances and strip- slot coupling for very efficient optical sensing,” Sensors, vol. 12, no. 3, pp. 2436-2455, Feb. 2012.

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Published

2021-03-08

How to Cite

[1]
Mohammad Y. Azab, Abed M. Nasr, S. S. A. Obayya, and Mohamed Farhat O. Hameed, “DNA Hybridization Detection based on Plasmonic Photonic Crystal Fiber”, ACES Journal, vol. 36, no. 3, pp. 229–234, Mar. 2021.

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