A human skin ultrasonic imaging to analyse its mechanical properties
DOI:
https://doi.org/10.13052/EJCM.18.105-116Keywords:
skin, finite elements, elastography, ultrasound, inverse method, behaviourAbstract
The analysis of the skin mechanical behaviour is a key-point for different field of investigation. As the skin is a complex structure, studies are usually based on inverse methods that compare experimental and finite element numerical results. Besides the considered behaviour law, one of the most important question concerns the geometrical aspects of the skin tissue. In this paper, it is shown how high frequency ultrasound imaging helps the calculation of skin mechanical parameters. The hypodermis influence is firstly discussed through elastographic analyses. A specific procedure to measure the dermis thickness is then proposed to highlight that such a measurement must be considered to draw reliable conclusions. The obtained results are finally discussed to point out the interest of such simplifications for the study of more complex behaviour laws.
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Agache P., Varchon D., Rochefort A., Humbert P., “Non invasive assessement of biaxial Young’s
modulus of human skin in vivo”, Journal of Biomechanics, vol. 25, 1992, p. 115-120.
Agache P., Physiologie de la peau et explorations fonctionnelles cutanées, Collection
explorations fonctionnelles humaines, 2000.
Cook T., Alexander H., Cohen M., “Experimental method for determining the 2-dimensional
mechanical properties of living human skin”, Medical and Biological Engineering and
Computing, vol. 15, 1977, p. 381-390.
Delalleau A., Josse G., Lagarde J.-M., Zahouani H., Bergheau J.-M., “A nonlinear elastic
behaviour to assess the mechanical parameters of human skin in vivo”, Skin Research and
Technology, accepted July 2007a, available online.
Delalleau A., Josse G., Lagarde J.-M., Zahouani H., Bergheau J-M., “Use of the Kalman
Filters for the analysis of the mechanical properties of human skin in vivo”, Inverse
Problems in Science and Engineering, accepted May 2007b.
Delalleau A., Analyse du comportement mécanique de la peau in vivo, PhD. Thesis, Jean
Monnet University, Saint-Etienne, France, 2007.
Diridollou S., Berson M., Vabre V., Black D., Karlsson B., Auriol F., Gregoire J.-M.,
Yvon C., Vaillan L., Gall Y., Patat F., “An in vivo method for measuring the mechanical
properties of the skin using ultrasound”, Ultrasound in Medecine and Biology, vol. 24,
n° 2, 1998, p. 215-224.
Diridollou S., Patat F., Gens F., Vaillant L., Black D., Lagarde J-M., Gall Y., Berson M., “In
vivo model of the mechanical properties of the human skin under suction”, Skin Research
and technology, vol. 6, n° 21, 2000, p. 221-225.
Hendricks F.M., Brokken D., van Eemeren J.T.W., Oomens C.W.J., Baijens F.P.T.,
Horsten J.B.A.M., “A numerical-experimental method to characterize the non-linear mechanical
behaviour of human skin”, Skin Research and Technology, vol. 9, 2003, p. 274-283.
Hendricks F.M., Brokken D., Oomens C.W.J., Bader D.L., Baijens F.P.T., « The relative
contributions of different skin layers to the mechanical behaviours of human skin in vivo
using suction experiments », Medical Engineering and Physics, vol. 28, 2006, p. 259-266.
Kass M., Witkin A., Terzopoulos D., “Snakes: active contour model”, International Journal
of Computer Vision, 1987, vol. 1, p. 321-331.
Khatyr F., Imberdis C., Vescovo P., Varchon D., Lagarde J-M., “Model of the viscoelastic
behaviour of skin in vivo and study of anisotropy”, Skin Research and Technology, vol. 10,
, p. 96-103.
Lagarde J.-M., George J., Soulcié R., Black D., “Automatic measurement of dermal thickness
from B-scan ultrasound images using active contours”, Skin Research and Technology,
vol. 11, n° 2, 2005, p. 79-90.
Mofid Y., Ossan F., Imberdis C., Patat F., “New elastographic algorithm for in vivo study of
mechanical behaviour of skin”, Proceedings of the international conference on
Ultrasounds Measurement and Imaging of Tissue Elasticity, 2004, p. 59.
Mofid Y., Ossant F., Imberdis C., Josse G., Patat F., “In vivo imaging of the skin under
stresses: Potential of high-frequency (20MHz) static 2-D elastography”, IEEE Transactions
on Ultrasonics, Ferrolectrics and Frequency Control, vol. 53, n° 5, 2006, p. 925-935.
Oomens C.W.J., van Campen D.H., Grootenboer H.J., “A mixture approach to the mechanics
of skin”, Journal of Biomechanics, vol. 20, n° 9, 1987, p. 877-885.
Ossant F., Patat F., Mofid Y., Gahagnon S., Josse G., “In vivo high frequency elastography
for mechanical behaviour of human skin under suction stress: elastograms and kinetics of
shear, axial and lateral strain fields”, IEEE Ultrasonics Symposium, 2006, p.1041-1044.
Pailler-Mattéi C., Caractérisations mécanique et Tribologique de la peau humaine in vivo,
PhD Thesis, Ecole Centrale de Lyon, France, 2004.
Panisset F., Varchon D., Agache P., “Non invasive measurement of stratum corneum Young’s
modulus in vivo”, XIVth Congress on Biomechanics, Paris, 1994.
Papir Y.S., Hsu H-H., Wildnauer R.H., “The mechanical properties of stratum corneum. I.
The effect of water and ambient temperature on the tensile properties of newborn rat
stratum corneum”, Biochimica et Biophysica acta, vol. 399, 1975, p. 170-180.
Samani A., Bishop J., Yaffe M., Plewes D.B., “Biomechanical 3-D Finite Element Modeling
of the Human Breast for MR/X-ray using MRI Data”, IEEE Transactions on Medical
Imaging, vol. 20, n° 4, 2001, p. 271-279.
Samani A., Bishop J., Luginbuhl C., Plewes D.B., “Measuring the elastic modulus of ex vivo
small tissue sample”, Physics in Medicine and Biology, vol. 48, 2003, p. 2183-2198.
Tran H.V., Charleux F., Ehrlacher A., Ho Ba Tho M-C., « Propriétés mécaniques multicouches
de la peau humain in vivo, modèle numérique anatomique », Proceedings of the 7e
Colloque National en Calcul des Structures de Giens, 2005.
Treloar L.R.G., “Stresses and birefringence in rubber subjected to general homogeneous
strain”, Proceedings of the Physical Society in London, vol. 60, p. 135-144, 1947.
Wilkes G.L., Brown I.A., Wildnauer R.H., “The biomechanical properties of skin”, Critical
Reviews in Bioengineering, vol. 1, n° 4, 1973, p. 453-495.