A reactive poroelastic model to predict the periprosthetic tissue healing
DOI:
https://doi.org/10.13052/EJCM.18.131-143Keywords:
biomathematics, osteointegration, poroelastic, finite element, osteoblastAbstract
Conditions influencing the implant osteointegration in the early post-operative period include the surgical technique and coupled mechanical and biochemical factors. We hypothesized that coupling deformable porous media mechanics to governing equations of cell migration, might help to predict the periprosthetic tissue healing and in particular the heterogeneous bone formation which is unfavourable to the implant survival. To proceed, a multiphasic model of porous tissue surrounding a loaded implant was coupled to osteoblast migration and immature bone deposit. A finite element resolution was implemented and the application concerned a canine implant. The sensitivity analysis using volume strain as variable showed that compression was rather unfavourable to homogenous distribution of periprosthetic bone healing.
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