OPTIMIZING PLANAR SOURCE DISTRIBUTIONS FOR DEEP POWER DEPOSITION IN BIOLOGICAL TISSUE

摘要

In non-invasive hyperthermia, penetration depth in high water content biological tissue can be increased up to 3 times using a focused instead of uniform surface electric field distribution. The focusing involves maximizing the field integral at a focal point by solving for the surface phase function which makes the integrand real and positive for all surface points. The resulting non-linear differential equation is solved in using a series approximation. A focused power deposition pattern is presented using this ideal planar distribution which is the theoretical optimum for high resolution hyperthermia cancer treatment. [Vol. 7, No. 2, pp. 97- 109 (1992), Special Issue on Bioelectromagnetic Computations]