Design, Development and Performance Evaluation of Nano Robot in Traditional Siddha Medicines for Cancer Treatment

Authors

  • Kaviarasu Balakrishnan Department of Electronics and Communication, Sathyabama Institute of Science and Technology, Chennai, India
  • Sivabalan Arumugam Rakuten Mobile Inc, Japan
  • Guna Magesan Institute of Advanced Research, Gandhinagar, Gujarat, India

DOI:

https://doi.org/10.13052/jicts2245-800X.833

Keywords:

Nano robot, medical robotics, artificial intelligence, cancer therapy, infection, breast cancer, Target drug delivery, Sootha Vennai, Siddha medicine

Abstract

This paper reports a design and fabrication of a functional nano robot “Sootha Vennai Parpamcutâvanai – Parpam – SVP” of 150-200 nm size which behaves more or less like a human physician in nano form inside the body. This nanorobot is a medicine which has artificial intelligence i.e. the distinguishing ability, decision making ability and some basic behavioral properties such as target detection ability, self-propelling capability and handling the infection in the case of breast cancer. This nanorobot can also aid in cancer therapy, site-specific or target drug delivery, and tissue repair.

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Author Biographies

Kaviarasu Balakrishnan, Department of Electronics and Communication, Sathyabama Institute of Science and Technology, Chennai, India

Kaviarasu Balakrishnan received M.Tech in Electronics and Communication Engineering from Pondicherry University, Pondicherry, India in 2000. He has 24 years of experience in Research and Academic. Presently he works as a Head of Research in Manushyaa Blossom Pvt Ltd, Chennai based Siddha Nano Bio Pharma company. He founded Dr Krishanmoorthy Foundation for Advanced Scientific Research, Vellore, a center for Nano Science in the year 2011. He has designed and synthesized more than 20 nano bio materials and discovered more than 300 processes of nano medicine synthesis using siddha medicine principles. He belonged to the tradition of Indian siddha system of medicine practitioners for more than 700 years. His is specialized in child immunisation using nano formulations. His research interest includes nano robotics, nano drug design, synthesis, delivery and nuclear physics.

Sivabalan Arumugam, Rakuten Mobile Inc, Japan

Sivabalan Arumugam received Ph.D in Electrical Engineering from Indian Institute of Technology Kanpur, India in 2008 and M.Tech degree from Pondicherry University, India, in 2000. He has 14 years of experience in Academic teaching and Research. Presently he works as Assistant General Manager for Research at NEC Mobile Network Excellence Center (NMEC), NEC Technologies India Pvt Ltd, Chennai. Prior joining NECI he was associated with ABB Global Services and Industries Limited, Bangalore as Associate Scientist. He has published more than 25 papers in various International Journals and Conferences and also participated in many National and International Conferences. In his current role, he is representing NEC for Global ICT Standards forum of India (GISFI). His research interest includes Next Generation Wireless Networks.

Guna Magesan, Institute of Advanced Research, Gandhinagar, Gujarat, India

Guna Magesan Director, International Operations, Manushyaa Blossom Pvt Ltd Till recently, Prof Guna Magesan was the Vice Chancellor of Institute of Advanced Research in Gandhinagar, Gujarat. He was the CEO of World Hindu Economic Forum (WHEF) in 2014 and now the Governing Council member of WHEF. Previously, he was the Professor and Head of Environmental Science Dept in Fiji National University. Prior to that, he was a Senior Scientist with New Zealand Govt research organization. He has been actively involved in social and community projects and he was made the Justice of the Peace in New Zealand.

References

Venkatesan, M. and Jolad, B. 2010. Nanorobots in cancer treatment. IEEE.

Ummat, A., Dubey, A., Sharma, G., Mavroidis, C., 2004. “Bio-nano-robotics: state of the art and future challenges,” Invited Chapter in The Biomedical Engineering Handbook, 3rd Edition, M. L. Yarmush (ed.), CRC Press.

Elvis S. Liu, On the scalability of agent-based modeling for medical nanorobotics, IEEE Proceedings of the 2015 Winter Simulation Conference, p1427–1435.

Lenaghan, S.C., Wang, Y., Xi, N., Fukuda, T., Tarn, T., Hamel, W.R., and Zhang, M. 2013. Grand challenges in bioengineered nanorobotics for cancer therapy. IEEE Transactions on Biomedical Engineering, 60(3): 667–673.

Requicha, A. A. G., 2003. “Nanorobots, NEMS, and nanoassembly”. Proceedings of the IEEE, Special Issue on Nanoelectronics and Nanoprocessing. Vol. 91, No. 11, pp. 1922–1933.

Patel, G.M., Patel, G.C., Patel, R.B., Patel, J.K., and Patel, M. 2006. Nanorobot: A versatile tool in nanomedicine. Journal of Drug Targeting, 14 (2): 63–67.

Mavroidis, C. and Ferreira, A. 2013. “Nanorobotics: Past, Present, and Future’. In Nanorobotics: Current Approaches and Techniques, edited by C. Mavroidis and A. Ferreira. New York: Springer.

Patrick Couvreur and Chirstine Vautheir, “Nanotechnoloogy : Intelligent Design to treat complex diseases”, Pharmaceutical Research, Vol. 23, No. 7, July 2006.

Cavalcanti, A., Shirinzadeh, B., and Kretly, L.C. 2008 June. Medical nanorobotics for diabetes control. Nanomedicine: Nanotechnology, Biology, and Medicine, 4 (2): 127–138.

http://siddhacouncil.com/

http://ayush.gov.in/

https://www.britannica.com/topic/Tamil-language

Garima Matela and Robina Aman, ‘Tin and OrganoTin (IV) complexes of thymol derivative derived from alanine : synthesis and characteristic spectral studies’, RASÃYAN J. Chem, Vol. 4, No. 3 (2011), 594–598.

Siddha vaidiya thirattu, http://www.manushyaablossom.com/siddha-lite rature.php

A. Laouini, C. Jaafar-Maalej, I. Limayem-Blouza, S. Sfar, C. Charcosset, and H. Fessi, “Preparation, Characterization and application of Liposomes: State of the Art”, Journal of Colloid Sciences and Biotechnology, Vol. 1, 147–168, 2012.

Pullipani, Pulipani-500, Thamari Publishers, Chennai.

Kowsigar, Kowsigar muni nool, Siddha Product Catalogue, IMPCOPS, Chennai.

Agathiyar, Agathiyar 12000, Thamarai Publishers, Chennai.

R. Shailaja, S Sugunthan (year). Concept of nano technology in Siddha medical literature. World Journal of Pharmaceutical Research. Volume 5, Issue 10, 276–284. Review Article ISSN 2277–7105.

K. Arunachalam, K. Rajamaheswari, K. Venkateswaran and K. Suryakumar (year). Anticancer potential of Siddha nano medicine Sangu Chunnam using Mtt assay against Hepg2 (liver cancer cell line). World Journal of Pharmacy and Pharmaceutical Sciences.Volume 8, Issue 3, 814–817.

K. Rajamaheswari, M. Pitchiah Kumar, V. Banumathi and S. Sudharsan (year). Standardization and analytical evaluation of novel Siddha formulation Singi. chenduram: An approach towards nano drug delivery system. Der Pharmacia Lettre, 2015, 7 (11):295–300.

Bogar, Bogar 700. Thamarai Noolagam, Chennai.

Bogar, Bogar Nigandu 1500, Thamarai Noolagam, Chennai.

Bogar, Bogar 7000,Thamarai Noolagam, Chennai.

Bogar, Bogar Janana Sagaram, Thamarai Noolagam, Chennai.

Soothamuni, Soothamuni Soothiram, Thamarai Noolagam, Chennai.

Pullasthiyar, Pullasthiyar Vadha Soothiram, Thamarai Noolagam, Chennai.

Medicinal Plant Of India, Vol-II, Tamil Nadu, S.N.YoganaRasimhan, Year 2000.

Agathiyar, Agathiyar 12000, Vol I, Thamarai Publishers, Chennai

Ying Wang, Ying Li, Jian Wu1, Qi Shen (2012). Characterisation and evaluation of self-microemulsifying drug delivery system of Brucea javanica oil. Micro & Nano Letters, 2012, Vol. 7, Iss. 3, pp. 256–261.

R. Manickavasagam, C. Senthamil Rajam (year). Siddha system and nano technology – a review. Inter-national Journal of Research in Pharmaceutical and Nano Sciences. 5(4), 2016, 235–238.

Agastiyar Kanma Kandam, Kowmathi Nool, Thamarai Publishers, Chennai.

Agastiyar Vaithiya Kaviyam-1500, Thamarai Publishers, Chennai.

Agastiyar Vagara Choothiram-200, Surukam-100, Thamarai Publishers, Chennai.

Karuvoorar Vatha Kaviyam 700, Thamarai Publishers, Chennai.

Scott C. Lenaghan, Yongzhong Wang, Ning Xi, Toshio Fukuda, Tzyhjong Tarn, William R. Hamel, and Mingjun Zhang (year). Grand challenges in bioengi-neered nanorobotics for cancer therapy. IEEE Transactions On Biomedical Engineering, VOL. 60, NO. 3, MARCH 2013.

Davis, M.E., Chen, Z.G. and Shin, G.M. 2008. Nano-particle therapeutics: An emerging treatment modality for cancer. Nature Rev Drug Discovery, vol 7. pp. 771–782.

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Published

2020-07-09

How to Cite

Balakrishnan, K., Arumugam, S., & Magesan, G. (2020). Design, Development and Performance Evaluation of Nano Robot in Traditional Siddha Medicines for Cancer Treatment. Journal of ICT Standardization, 8(3), 217–234. https://doi.org/10.13052/jicts2245-800X.833

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